KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PA2G4
All Species:
28.48
Human Site:
S252
Identified Species:
52.22
UniProt:
Q9UQ80
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UQ80
NP_006182.2
394
43787
S252
T
I
Y
K
R
D
P
S
K
Q
Y
G
L
K
M
Chimpanzee
Pan troglodytes
XP_001169382
372
41245
S230
T
I
Y
K
R
D
P
S
K
Q
Y
G
L
K
M
Rhesus Macaque
Macaca mulatta
XP_001114067
394
43710
S252
T
I
Y
K
R
D
P
S
K
Q
Y
G
L
K
M
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P50580
394
43680
S252
T
I
Y
K
R
D
P
S
K
Q
Y
G
L
K
M
Rat
Rattus norvegicus
NP_001004206
394
43638
S252
T
I
Y
K
R
D
P
S
K
Q
Y
G
L
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520977
286
31862
A160
L
K
M
K
T
S
R
A
F
F
S
E
V
E
R
Chicken
Gallus gallus
XP_423059
343
38447
Y217
A
G
Q
R
T
T
I
Y
K
R
D
P
S
K
Q
Frog
Xenopus laevis
NP_001085830
390
43452
T252
T
I
Y
K
R
D
P
T
K
Q
Y
G
L
K
M
Zebra Danio
Brachydanio rerio
NP_001002070
392
43305
S251
T
I
Y
K
R
D
P
S
K
Q
Y
G
L
K
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647984
391
42755
E251
V
S
I
Y
K
K
S
E
E
N
Y
M
L
K
M
Honey Bee
Apis mellifera
XP_395683
387
43816
E251
T
I
F
K
K
T
E
E
T
Y
Q
L
K
L
K
Nematode Worm
Caenorhab. elegans
NP_500311
391
43014
Q263
T
V
F
R
K
N
E
Q
V
S
Y
Q
L
K
M
Sea Urchin
Strong. purpuratus
XP_780193
402
44856
D251
V
T
V
Y
K
R
T
D
E
T
Y
Q
L
K
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.4
99.7
N.A.
N.A.
98.9
98.9
N.A.
55.3
80.7
89.5
84.2
N.A.
54
56.8
48.4
60.2
Protein Similarity:
100
94.4
99.7
N.A.
N.A.
99.2
99.4
N.A.
60.4
84.5
95.4
91.1
N.A.
70.3
71.8
68.2
74.3
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
6.6
13.3
93.3
100
N.A.
26.6
20
33.3
26.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
26.6
26.6
100
100
N.A.
40
33.3
66.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
54
0
8
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
16
16
16
0
0
8
0
8
0
% E
% Phe:
0
0
16
0
0
0
0
0
8
8
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
54
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
62
8
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
70
31
8
0
0
62
0
0
0
8
85
8
% K
% Leu:
8
0
0
0
0
0
0
0
0
0
0
8
77
8
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
77
% M
% Asn:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
54
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
8
0
54
8
16
0
0
8
% Q
% Arg:
0
0
0
16
54
8
8
0
0
8
0
0
0
0
8
% R
% Ser:
0
8
0
0
0
8
8
47
0
8
8
0
8
0
0
% S
% Thr:
70
8
0
0
16
16
8
8
8
8
0
0
0
0
0
% T
% Val:
16
8
8
0
0
0
0
0
8
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
54
16
0
0
0
8
0
8
77
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _